BioMedUSA - The Center for Sharing and Licensing of Biological Research Materials and Related Technologies

BioMedUSA

BioMedUSA serves as a global open access hub for sharing and licensing of Biological Research Materials and related technologies.

We connect individual biomedical researchers and institutional Technology Transfer Offices owning proprietary Biological Research Materials and related technologies with scientists and institutions looking for available to share or license biological materials and technologies.

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Browse the Available to Share or License Biological Research Materials and Related Technologies

 
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Combined use of IKK inhibitors with β-adrenergic receptor agonists for the treatment of obesity and metabolic disorders

Combined use of IKK inhibitors with β-adrenergic receptor agonists for the treatment of obesity and metabolic disorders

Technology #6084 Combined use of IKK inhibitors with β-adrenergic receptor agonists for the treatment of obesity and metabolic disorders. Studies conducted at the University of Michigan show that the induction of IKKε and TBK1 reduces…
02/15/2015
Ann Arbor
MI
Total views: 141
Rapid Test for VZV in Saliva

Rapid Test for VZV in Saliva

Background The highly contagious VZV virus attacks first as chickenpox, occurring in over 4 million people every year. Over 95% of Americans contract the disease before the age of 18. Of these, 1 in 7…
02/13/2015
Boulder
CO
Total views: 105
Mouse model for malignant melanoma

Mouse model for malignant melanoma

Utility: Carcinogen application on the ear and the ultraviolet exposure on the tail induces malignant melanoma. A tendency to develop highly invasive and/or metastatic melanoma may be induced in these animals by further applying carcinogen…
02/11/2015
Boulder
CO
Total views: 98
ALK/RET Fusions as Lung Cancer Diagnostic and Therapeutic Target

ALK/RET Fusions as Lung Cancer Diagnostic and Therapeutic Target

Background Lung cancer remains a leading cause of mortality in cancer worldwide and is mostly represented by non-small cell lung cancer (NSCLC). NSCLC is being increasingly recognized as a heterogeneous set of diseases based both…
02/13/2015
Boulder
CO
Total views: 95
A Protein Platform For Utilitarian Vaccine Development

A Protein Platform For Utilitarian Vaccine Development

Portfolio Summary: Garcea HPV Vaccine Technologies Summary ♦ HPV capsomeres for use in vaccines which protect against or eradicate human HPV infection, and in diagnosis and serotyping of HPV infection. ♦ Therapeutic and next-gen prophylactic…
02/13/2015
Boulder
CO
Total views: 93
Transgenic mice with myr-AKT

Transgenic mice with myr-AKT

Utility: Useful for testing drugs that inhibit Akt, testing for oncogenes that can accelerate tumor formation in mammary gland or testing chemical carcinogens that induce mammary gland cancer. Disclaimer: information provided by the University of…
02/11/2015
Boulder
CO
Total views: 92
Generation of long-lived mouse mutants by chemical mutagenesis in embryonic stem cells

Generation of long-lived mouse mutants by chemical mutagenesis in embryonic stem cells

Utility: Compound screening for anti-aging agents with an emphasis on antioxidation pathways. Disclaimer: information provided by the University of Colorado Technology Transfer Office, reproduced with permission.
02/11/2015
Boulder
CO
Total views: 91
Landscape Phage as Bio-Recognition Elements in Biosensors

Landscape Phage as Bio-Recognition Elements in Biosensors

Landscape Phage as Bio-Recognition Elements in Biosensors* Overview Auburn University is seeking licensees for a technology using landscape filamentous phage as a bio-selective element for biosensors. As superior substitutes for antibodies, phage demonstrate many features…
02/08/2015
Auburn
AL
Total views: 91
Mutant cholera holotoxin as a powerful vaccine adjuvant

Mutant cholera holotoxin as a powerful vaccine adjuvant

Summary of Information: - Four mutant, immunogenic forms of cholera holotoxin - Reduced toxicity compared to wild-type CT - Powerful immune system stimulators, useful as vaccine adjuvant in any type of vaccine (cancer, infectious disease,…
02/13/2015
Boulder
CO
Total views: 88
Mouse Mutant with a Phenotype of Resistance to Mouse Hepatitis Viral Infections

Mouse Mutant with a Phenotype of Resistance to Mouse Hepatitis Viral Infections

Utility: Study of viral hepatitis. Disclaimer: information provided by the University of Colorado Technology Transfer Office, reproduced with permission.
02/11/2015
Boulder
CO
Total views: 87
Protein Expression Profiles of Breast Cancer in Tissue and in Blood

Protein Expression Profiles of Breast Cancer in Tissue and in Blood

Novel Protein Biomarker for Differential Diagnosis of Early Stage Breast Cancer Background Apart from non-melanoma skin cancer, breast cancer is the most common form of cancer in women. Each year in the U.S., about 200,000…
02/13/2015
Boulder
CO
Total views: 86
Modified nanoparticle-based therapeutics for better absorption in the gastrointestinal tract

Modified nanoparticle-based therapeutics for better absorption in the gastrointestinal tract

Background Gold nanoparticles are rapidly gaining ground in the biomedical field, offering new ways to study, diagnose, and treat diseases. Gold-based nanoparticles are appealing because they are inert and non-toxic, are tunable across the visible-near…
02/13/2015
Boulder
CO
Total views: 85
Congenic mouse model for lupus

Congenic mouse model for lupus

B6.Nba2 congenic mice as a model for spontaneous lupus-like disease development. Utility: Genes Immun. 2007 Dec;8(8):653-62. Epub 2007 Sep 20. Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2…
02/11/2015
Boulder
CO
Total views: 83
Transgenic mice with prolactin mutant

Transgenic mice with prolactin mutant

Utility: Useful for testing drugs that inhibit mammary cancer, for testing for oncogenes that can accelerate tumor formation in mammary gland or for chemical carniogens that induce mammary gland cancer. Disclaimer: information provided by the…
02/11/2015
Boulder
CO
Total views: 83
Stabilized Liquid Antibody Formulations for Parenteral Administration

Stabilized Liquid Antibody Formulations for Parenteral Administration

Background Instabilities of proteins are a major obstruction to commercial development of protein drugs. In particular, protein aggregation, which often arises because of this instability, is a major obstacle in all phases of drug development.…
02/13/2015
Boulder
CO
Total views: 81
Homeobox Genes and Novel Cancer Therapeutics

Homeobox Genes and Novel Cancer Therapeutics

Homeobox Genes and Novel Cancer Therapeutics: Heide Ford Portfolio Summary Background Through recent discoveries in cancer biology, it has become increasingly evident that tumor growth and normal development share many properties. Both processes involve alterations…
02/13/2015
Boulder
CO
Total views: 79
Prediction of Survival and Response to Therapy in Cancer by Measuring MicroRNA

Prediction of Survival and Response to Therapy in Cancer by Measuring MicroRNA

Background Lung carcinoma remains the leading cause of cancer death worldwide for both men and women. Non-small cell lung cancer (NSCLC) accounts for approximately 86% of lung cancer cases and presents in advanced stage about…
02/13/2015
Boulder
CO
Total views: 79
RNA-based drug delivery platform

RNA-based drug delivery platform

RNA-based drug delivery platform* Overview Auburn University is seeking a licensee or development partner for a versatile drug delivery platform that can control and modulate the release of a single therapeutic or multiple therapeutics in…
02/04/2015
Auburn
AL
Total views: 77
GLEPP1

GLEPP1

Technology #0872 - Background The kidney is the organ in vertebrates chiefly responsible for eliminating wastes from the blood and regulating the blood’s chemical balance. The anatomy of the kidney and the architecture of the…
02/25/2015
Ann Arbor
MI
Total views: 73
Biomarker for Selection/Modulation of TRAIL and other Cancer Therapies

Biomarker for Selection/Modulation of TRAIL and other Cancer Therapies

Background Through recent discoveries in cancer biology, it has become increasingly evident that tumor growth and normal development share many properties. Both processes involve alterations in cell proliferation and differentiation, alterations in cell death, neovascularization,…
02/13/2015
Boulder
CO
Total views: 72
Liquid Crystal Based Detection of Nucleic Acid Hybridization at the Fluid Interface

Liquid Crystal Based Detection of Nucleic Acid Hybridization at the Fluid Interface

Detection of Nucleic Acid Hybridization Using Liquid Crystals Technology and Applications This technology describes methods for detecting hybridization of nucleic acids using liquid crystals (LC) and cationic surfactant monolayers without the need for molecular labels…
02/12/2015
Boulder
CO
Total views: 72
Diagnosis and Treatment of Myocardial Failure using Myosin Heavy Chains

Diagnosis and Treatment of Myocardial Failure using Myosin Heavy Chains

Background Heart failure is a pathophysiological state in which the heart fails to pump blood at a rate required by the metabolizing tissues of the body. About 95% of the time, heart failure is caused…
02/15/2015
Boulder
CO
Total views: 71
Treatment of leukemia with "super-competent" hematopoietic stem/progenitor cells

Treatment of leukemia with "super-competent" hematopoietic stem/progenitor cells

Utility: Immunology (manipulates expression of regulatory genes in hematopoietic cells). Disclaimer: information provided by the University of Colorado Technology Transfer Office, reproduced with permission.
02/11/2015
Boulder
CO
Total views: 69
Adenoviral-Mediated Gene Transfer Into Lymphocytes: Advancing Genetic Study of the Immune System

Adenoviral-Mediated Gene Transfer Into Lymphocytes: Advancing Genetic Study of the Immune System

tCAR Expression in Lymphocytes: Advancing Genetic Study of the Immune System Background Bacterial and viral Infection is the number one cause of human disease, ranging in severity from the common cold to the life threatening…
02/10/2015
Boulder
CO
Total views: 68
Diagnostic Screen to Distinguish Between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Diagnostic Screen to Distinguish Between Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Background Irritable Bowel Syndrome (IBS) is a condition that produces some symptoms similar to Inflammatory Bowel Disease (IBD). However, they are not the same condition and they involve very different diagnostic criteria and treatments. IBS…
02/13/2015
Boulder
CO
Total views: 67
 
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